Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025369 | 1.00 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL230664 | 1.00 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL30129192 | 0.87 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL26188631 | 0.87 | LMNA (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28512921 | 0.85 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28507362 | 0.85 | POLB (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Etocrylene SCHEMBL39390 | 0.84 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8076180 | 0.84 | MAPT (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Etocrylene SCHEMBL1768864 | 0.84 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8076184 | 0.84 | MAPT (0.56) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103261-A1 | CRYSTAL FORM B OF ETHYL 2-CYANO-3-AMINO-3-PHENYLACRYLATE, PREPARATION METHOD, AND APPLICATION | 江苏省农药研究所股份有限公司 | 2023-06-15 | — | — | WO | claimed |
| CN-113912519-B | Crystal form B of 2-cyano-3-amino-3-ethyl phenylacrylate, preparation method and application | 江苏省农药研究所股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-113912519-A | Crystal form B of 2-cyano-3-amino-3-ethyl phenylacrylate, preparation method and application | 江苏省农药研究所股份有限公司 | 2022-01-11 | — | — | CN | claimed |
| EP-3010893-B1 | ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-10-02 | — | — | EP | claimed |
| EP-3395171-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-10-31 | — | — | EP | claimed |
| EP-3010889-B1 | ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-10-03 | — | — | EP | claimed |
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | claimed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | claimed |
| US-20160145235-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-26 | — | — | US | claimed |
| US-20160130240-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | US | claimed |
| EP-2793578-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience AG (DE) | 2014-10-29 | — | — | EP | claimed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | claimed |
| WO-2014095979-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-26 | — | — | WO | claimed |
| WO-2013092350-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2013-06-27 | — | — | WO | claimed |
| EP-2606726-A1 | N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | claimed |
| EP-2590511-A2 | ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-15 | — | — | EP | claimed |
| EP-2494867-A1 | Halogen-substituted compounds in combination with fungicides | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | claimed |
| EP-2467367-A1 | 3-TRIAZOLYLPHENYL-SUBSTITUTED SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES | Bayer CropScience AG (DE) | 2012-06-27 | — | — | EP | claimed |
| WO-2012004221-A2 | ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | claimed |
| WO-2011020567-A1 | 3-TRIAZOLYLPHENYL-SUBSTITUTED SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | AFF4, ARSA, AFF1 | MEN1 4026/4885KMT2A 2592/4885ALDH1A1 1348/4885 |
| US-20160130240-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | ARSA, SQOR, AHR | MEN1 4833/4885KMT2A 2528/4885ALDH1A1 101/4885 |
| US-20160145235-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | ARSA, SQOR, AHR | MEN1 4840/4885KMT2A 2505/4885ALDH1A1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.