Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613032 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL8250667 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL3754398 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRPOLBCYP2C19HPGD | |
| SCHEMBL9574420 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL2398421 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL15682609 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGD | |
| SCHEMBL31628174 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL2064880 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL9826058 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL2287025 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034740-A1 | (R)-3-(N,N-DIMETHYLAMINO)PYRROLIDINE DERIVATIVES | PALAU PHARMA, S.A. (ES) | 2010-04-01 | — | — | WO | disclosed |