Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613032 | 0.91 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL2398421 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL3263548 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL9826058 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL31628174 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL2287025 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL29437308 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL124981 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL11225404 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL4506185 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167122-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | WYETH | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167122-A1 | Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands | HTR6, HTR1A, HTR2C | ALDH1A1 668/4885TSHR 296/4885HPGD 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.