Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15682609 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGD | |
| SCHEMBL5185195 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL10482069 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL2398421 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGD | |
| SCHEMBL3263548 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL28613032 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGD | |
| SCHEMBL8250667 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGD | |
| SCHEMBL31628174 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGD | |
| SCHEMBL9826058 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGD | |
| SCHEMBL2287025 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058389-A1 | Carboxamides | CBR3, CBR1, H1-10 | ALDH1A1 1944/4885TSHR 464/4885HPGD 3403/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | ALDH1A1 1079/4885TSHR 1602/4885HPGD 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.