Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263577 | 1.00 | GBA1 (0.50) | GBA1HTR6SLC22A1PRCPMEN1 | |
| SCHEMBL11072045 | 0.83 | MEN1 (0.53) | GBA1HTR6SLC22A1PRCPMEN1 | |
| SCHEMBL9311027 | 0.78 | HTR6 (0.75) | HTR6SLC22A1PRCPDDB1CRBN | |
| SCHEMBL8515554 | 0.77 | GBA1 (0.53) | GBA1DDB1CRBNPOLBMAOB | |
| Hydrochloric Acid SCHEMBL6677769 | 0.75 | GBA1 (0.51) | GBA1DDB1CRBNPOLBMAOB | |
| Hydrochloric Acid SCHEMBL11851140 | 0.75 | PRCP (0.68) | GBA1SLC22A1PRCPMEN1CYP3A4 | |
| SCHEMBL644078 | 0.75 | HTR6 (0.61) | HTR6SLC22A1PRCP | |
| SCHEMBL1248364 | 0.74 | BCHE (0.41) | MEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL3258819 | 0.71 | MEN1 (0.69) | PRCPMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL3258817 | 0.71 | MEN1 (0.69) | PRCPMEN1CYP3A4CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |