Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445623 | 0.82 | SLC6A2 (0.62) | SLC6A2CDC7CDK2ROCK1 | |
| SCHEMBL9445652 | 0.78 | SLC6A2 (0.53) | SLC6A2CDC7CDK2ROCK1CDK4 | |
| SCHEMBL4108710 | 0.77 | RAB9A (0.50) | KMT2AMEN1NPC1RAB9APKM | |
| SCHEMBL3139425 | 0.74 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL9445587 | 0.73 | SLC6A2 (0.48) | SLC6A2KMT2AMEN1NPC1CDK2 | |
| SCHEMBL3733770 | 0.72 | CA12 (0.42) | KMT2AMEN1MAPK10GFERNPC1 | |
| SCHEMBL6628128 | 0.72 | SLC6A2 (0.73) | SLC6A2KMT2AMEN1RAB9ACDK4 | |
| SCHEMBL9311675 | 0.71 | ADRA2A (0.54) | KMT2AMEN1MAPK10GFERNPC1 | |
| SCHEMBL7610186 | 0.70 | SLC6A2 (0.69) | SLC6A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6859755 | 0.70 | MEN1 (0.48) | KMT2AMEN1MAPK10GFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | claimed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | claimed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |
| JP-6001787-A | — | — | None | — | — | JP | disclosed |
| JP-7053376-A | — | — | None | — | — | JP | disclosed |
| EP-2766017-B1 | METHODS FOR TREATING A STROKE-RELATED SENSORIMOTOR IMPAIRMENT USING AMINOPYRIDINES | ACORDA THERAPEUTICS INC (US) | 2020-07-01 | — | — | EP | disclosed |
| JP-2010120958-A | METHOD OF TREATING OF DEMYELINATING DISEASE OR CONDITION | AVENTIS PHARMACEUTICALS INC | 2010-06-03 | — | — | JP | disclosed |
| US-20090281147-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090281147-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090270458-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | AVENTIS PHARMACEUTICALS INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090270458-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | AVENTIS PHARMACEUTICALS INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-5185350-A | For Alzheimer*s, memory dysfunctions, antidepressants, antiinflammatory agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-02-09 | — | — | US | disclosed |
| US-5185350-A | For Alzheimer*s, memory dysfunctions, antidepressants, antiinflammatory agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0376155-B1 | N-PYRIDINYL-9H-CARBAZOL-9-AMINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5039811-A | Analgesics, antidepressants, memory activators; condensation, reduction | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0287982-A3 | N-(PYRIDINYL)-1H-INDOL-1-AMINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4970218-A | ANALGESIC, ANTIDEPRESSANT, MEMORY ENHANCEMENT | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4880822-A | COGNITION ACTIVATORS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0287982-A2 | N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281147-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | PMP22, BDKRB1, BDKRB2 | SLC6A2 1049/4885KMT2A 3564/4885MEN1 1949/4885 |
| US-20090270458-A1 | METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS | PMP22, BDKRB1, BDKRB2 | SLC6A2 1049/4885KMT2A 3564/4885MEN1 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.