Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906443 | 0.81 | RAB9A (0.53) | HSD17B10HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL27140315 | 0.80 | PDE4D (0.59) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL10860621 | 0.79 | KDM4E (0.51) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL24906442 | 0.79 | PDE4D (0.53) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL22397138 | 0.79 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL30964220 | 0.77 | MAPT (0.49) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL28802616 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL599593 | 0.77 | ALDH1A1 (0.54) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 | |
| SCHEMBL3260996 | 0.76 | PDE4D (0.69) | CYP1A2CYP2C9CYP2C19PDE4DHPGD | |
| SCHEMBL24757285 | 0.76 | MAPT (0.48) | CYP1A2CYP2C9CYP2C19PDE4DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |