Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | FLT3 | P36888 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | STK17B | O94768 | 1/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14124819 | 0.91 | NPC1 (0.84) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL11109735 | 0.90 | NPC1 (0.81) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL244107 | 0.88 | FLT3 (1.00) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL31061078 | 0.88 | FLT3 (1.00) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL11843224 | 0.88 | NPC1 (0.78) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL19380254 | 0.88 | NPC1 (0.78) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL8761650 | 0.86 | NPC1 (1.00) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL8708182 | 0.86 | NPC1 (0.76) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL2507064 | 0.86 | NPC1 (0.76) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL29848148 | 0.86 | NPC1 (0.76) | NPC1RAB9AMAPK1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2859069-B1 | METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT | FERRARA MARCELLO (IT) | 2020-10-14 | — | — | EP | claimed |
| CN-108484546-A | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2018-09-04 | — | — | CN | claimed |
| US-9328300-B2 | Method, apparatus and chemical products for treating petroleum equipment | FERRARA MARCELLO (IT) | 2016-05-03 | — | — | US | claimed |
| EP-2859069-A1 | METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT | Ferrara, Marcello (IT) | 2015-04-15 | — | — | EP | claimed |
| WO-2013156228-A1 | METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT | FERRARA MARCELLO (IT) | 2013-10-24 | — | — | WO | claimed |
| US-20130270157-A1 | METHOD, APPARATUS AND CHEMICAL PRODUCTS FOR TREATING PETROLEUM EQUIPMENT | FERRARA MARCELLO (IT) | 2013-10-17 | — | — | US | claimed |
| WO-1995020637-A2 | HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS | MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) | 1995-08-03 | — | — | WO | claimed |
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | UNIV YALE (US) | 2024-01-18 | — | — | US | disclosed |
| CN-117105891-A | Synthesis method of benzofuran compound promoted by DBDMH | 河南科技大学 | 2023-11-24 | — | — | CN | disclosed |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2023149549-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |
| CN-112812084-B | Synthetic method of benzofuran compound | 温州大学新材料与产业技术研究院 | 2022-08-09 | — | — | CN | disclosed |
| US-4094845-A | PLANTS, CARBOXYLATED HYDROPHILIC ACRYLIC POLYMER, CROSSLINKING AGENT AND AN ULTRAVIOLET ABSORBER | UNITED STATES TRADING INTERNATIONAL, INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4082884-A | METHOD OF REDUCING FOULING OF MARINE STRUCTURES AND COATED STRUCTURE THEREOF | UNITED STATES TRADING INTERNATIONAL, INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4049869-A | CROSSLINKING A CARBOXYLATED HYDROPHILIC ACRYLIC POLYMER | UNITED STATES TRADING INTERNATIONAL, INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | NPC1 1290/4885RAB9A 3888/4885MAPK1 4213/4885 |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | NPC1 1290/4885RAB9A 3888/4885MAPK1 4213/4885 |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | NSUN2, RBM22, RNGTT | NPC1 1290/4885RAB9A 3888/4885MAPK1 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.