Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386981 | 0.81 | PTGES (0.43) | L3MBTL1GAAPTGESPOLBIDO1 | |
| SCHEMBL3263121 | 0.78 | MAPK1 (0.43) | L3MBTL1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL3261016 | 0.75 | KDM4E (0.43) | L3MBTL1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL24687080 | 0.75 | — | — | |
| SCHEMBL12554990 | 0.74 | KMT2A (0.49) | GAAKMT2APOLBIDO1ALDH1A1 | |
| SCHEMBL31310138 | 0.72 | IDO1 (0.44) | KMT2APOLBIDO1ALDH1A1LDHA | |
| SCHEMBL8561566 | 0.71 | CA12 (0.43) | KMT2APOLBHPGDMAPTKDM4E | |
| Ether SCHEMBL9486848 | 0.70 | DPP4 (0.48) | L3MBTL1GAAKMT2APOLBALDH1A1 | |
| SCHEMBL11967290 | 0.70 | POLB (0.41) | L3MBTL1KMT2APOLBIDO1ALDH1A1 | |
| SCHEMBL11624756 | 0.69 | HSP90AA1 (0.45) | L3MBTL1GAAKMT2APOLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |