Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 6/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046425 | 0.72 | CA12 (0.80) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3263121 | 0.71 | MAPK1 (0.43) | MAPTMEN1POLBHPGDTSHR | |
| SCHEMBL5464526 | 0.71 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3264012 | 0.71 | L3MBTL1 (0.51) | MAPTMEN1POLBHPGDKMT2A | |
| SCHEMBL6217782 | 0.70 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3263726 | 0.70 | TSHR (0.42) | MAPTMEN1HPGDTSHRKMT2A | |
| SCHEMBL8561558 | 0.68 | CA12 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8569093 | 0.68 | ALOX15 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10015554 | 0.65 | CA1 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15524700 | 0.65 | CA12 (0.44) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873318-A1 | HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997012879-A1 | HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-10 | — | — | WO | disclosed |