Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | FES | P07332 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261016 | 0.83 | KDM4E (0.43) | MAPK1PRKAA1ALDH1A1HPGDNPC1 | |
| SCHEMBL1386673 | 0.81 | SQOR (0.49) | MAPK1CDC7CDK1CDK2DYRK1A | |
| SCHEMBL1384959 | 0.79 | SQOR (0.51) | MAPK1CDC7PLK4CHEK1CHUK | |
| SCHEMBL6971232 | 0.79 | AKT1 (0.39) | MAPK1CDC7PLK4CHEK1CHUK | |
| SCHEMBL3264012 | 0.78 | L3MBTL1 (0.51) | CDK2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL8003068 | 0.78 | LSS (0.53) | MAPK1CDC7PLK4CHEK1CHUK | |
| SCHEMBL10432295 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4ETP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL29504118 | 0.74 | AXL (0.39) | MAPK1CDC7PLK4CHEK1CHUK | |
| SCHEMBL25274257 | 0.73 | METAP2 (0.43) | MAPK1CDC7PLK4CHEK1CHUK | |
| SCHEMBL28195540 | 0.73 | L3MBTL1 (0.47) | ALDH1A1HPGDMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |