Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578632 | 0.86 | LMNA (0.67) | LMNAHSP90AA1KMT2ATDP1SLC6A2 | |
| SCHEMBL6762297 | 0.86 | TDP1 (0.58) | LMNAHSP90AA1KMT2ATDP1SLC6A2 | |
| SCHEMBL10708477 | 0.82 | LMNA (0.81) | LMNAHSP90AA1KMT2ATDP1SLC6A2 | |
| SCHEMBL6698424 | 0.81 | NPC1 (0.47) | LMNAHSP90AA1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9696121 | 0.80 | KMT2A (0.73) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL10344103 | 0.80 | KMT2A (0.73) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL6565953 | 0.80 | TDP1 (0.70) | LMNAHSP90AA1KMT2ATDP1SLC6A2 | |
| SCHEMBL10574439 | 0.79 | L3MBTL1 (0.59) | LMNAHSP90AA1KMT2ATDP1MEN1 | |
| SCHEMBL8198304 | 0.79 | KMT2A (0.77) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL30438068 | 0.79 | KMT2A (0.58) | LMNAHSP90AA1KMT2ATDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100040738-A1 | Extension Of Beverage Shelf-Stability By Solute-Ligand Complexes | PEPSICO., INC. (US) | 2010-02-18 | — | — | US | disclosed |