Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928660 | 0.81 | ALOX15 (0.58) | KDM4EALOX15KMT2AIGFBP3IGFBP5 | |
| SCHEMBL3264169 | 0.78 | KDM4E (0.62) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL6080167 | 0.76 | KDM4E (0.48) | KDM4ETSHRKMT2AIGFBP3IGFBP5 | |
| SCHEMBL6605390 | 0.75 | FDPS (0.38) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL6080368 | 0.74 | KDM4E (0.46) | KDM4EALOX15TSHRKMT2AMMP2 | |
| Hydrochloric Acid SCHEMBL6080849 | 0.74 | FDPS (0.37) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL6079288 | 0.73 | KDM4E (0.51) | KDM4EKMT2AP2RX3IGFBP3IGFBP5 | |
| SCHEMBL30744928 | 0.73 | GRM2 (0.43) | KDM4EALOX15P2RX3HCAR2IGFBP3 | |
| SCHEMBL6080099 | 0.72 | KDM4E (0.47) | KDM4ETSHRKMT2AIGFBP3IGFBP5 | |
| SCHEMBL6080124 | 0.72 | PLAUR (0.45) | KDM4ETDP1KMT2AP2RX3IGFBP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885TDP1 2264/4885ALOX15 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.