Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265821 | 0.86 | ALDH1A1 (0.48) | GAANR4A2TSHRHTTMAPT | |
| SCHEMBL3261338 | 0.83 | NR4A2 (0.56) | NR4A2MAPTCYP1A2CYP2C19KMT2A | |
| SCHEMBL23863063 | 0.74 | NR4A2 (0.54) | GAANR4A2TSHRHTTMAPT | |
| SCHEMBL3263699 | 0.71 | GAA (0.48) | GAANR4A2TSHRHTTMAPT | |
| SCHEMBL3263240 | 0.71 | NR4A2 (0.53) | GAANR4A2MAPTCYP1A2CYP2C19 | |
| SCHEMBL17670781 | 0.70 | TDP1 (0.47) | GAANR4A2TSHRHTTMAPT | |
| SCHEMBL3263777 | 0.70 | KDM4E (0.51) | NR4A2HTTMAPTKMT2AMEN1 | |
| SCHEMBL3982399 | 0.69 | GSK3B (0.56) | GAANR4A2MAPTCYP1A2CYP2C19 | |
| SCHEMBL20570224 | 0.68 | MAPT (0.58) | GAANR4A2TSHRHTTMAPT | |
| SCHEMBL21465541 | 0.67 | MAPT (0.57) | GAANR4A2TSHRHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |