Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261338 | 0.80 | NR4A2 (0.56) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL7218658 | 0.75 | NR4A2 (0.59) | GAAGLAALDH1A1HPGDMEN1 | |
| SCHEMBL3265821 | 0.74 | ALDH1A1 (0.48) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7410285 | 0.73 | GAA (0.50) | GAAGLAALDH1A1HPGDMEN1 | |
| SCHEMBL3264185 | 0.71 | GAA (0.46) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28025010 | 0.71 | GAA (0.53) | GAAGLAALDH1A1HPGDMEN1 | |
| SCHEMBL3263240 | 0.68 | NR4A2 (0.53) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3263777 | 0.68 | KDM4E (0.51) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL8379922 | 0.67 | ALDH1A1 (0.56) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28834767 | 0.66 | KDM4E (0.58) | GAAGLAALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |