Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261338 | 0.88 | NR4A2 (0.56) | KDM4EMAPTALOX5ALDH1A1HSD17B10 | |
| SCHEMBL7459854 | 0.80 | KDM4E (0.58) | KDM4EMAPTTDP1ALOX5ALDH1A1 | |
| SCHEMBL7311543 | 0.79 | KDM4E (0.57) | KDM4EMAPTTDP1ALOX5ALDH1A1 | |
| SCHEMBL3264074 | 0.78 | KMT2A (0.53) | KDM4EMAPTTDP1ALOX5ALDH1A1 | |
| SCHEMBL4625769 | 0.77 | KDM4E (0.51) | KDM4EMAPTTDP1ALDH1A1NR4A2 | |
| SCHEMBL3263240 | 0.75 | NR4A2 (0.53) | KDM4EMAPTALOX5ALDH1A1HSD17B10 | |
| SCHEMBL3265821 | 0.70 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1HSD17B10NR4A2 | |
| SCHEMBL16433366 | 0.70 | KDM4E (0.66) | KDM4EMAPTTDP1ALDH1A1HSD17B10 | |
| SCHEMBL570154 | 0.70 | NR4A2 (0.67) | KDM4EMAPTTDP1ALDH1A1HSD17B10 | |
| SCHEMBL6964299 | 0.69 | KDM4E (0.57) | KDM4EMAPTTDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |