Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463293 | 0.76 | MAPT (0.44) | TAAR1ALOX15ALDH1A1MAPK1MAOB | |
| SCHEMBL17723819 | 0.75 | CA1 (0.47) | HTR2ATAAR1CYP2A6CA1CA2 | |
| SCHEMBL7676409 | 0.75 | TAAR1 (0.60) | HTR2ATAAR1CYP2A6CA1CA2 | |
| SCHEMBL15558948 | 0.74 | TAAR1 (0.54) | TAAR1ALDH1A1HTR2CIDO1MAOB | |
| SCHEMBL4459928 | 0.74 | LOXL2 (0.46) | HTR2ATAAR1HTR2CHTR2BIDO1 | |
| SCHEMBL6641361 | 0.74 | ESR1 (0.46) | TAAR1CA1CA2CA5ACA9 | |
| SCHEMBL4976900 | 0.74 | TSHR (0.46) | HTR2ATAAR1CYP2A6ALDH1A1MAPK1 | |
| SCHEMBL6060758 | 0.74 | TSHR (0.48) | HTR2ATAAR1CYP2A6CA1CA2 | |
| SCHEMBL150158 | 0.72 | TAAR1 (0.56) | HTR2ATAAR1CYP2A6ALDH1A1 | |
| SCHEMBL7839746 | 0.72 | HTR2C (0.38) | HTR2ATAAR1CYP2A6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028389-A1 | IMAGE-GUIDED ENERGY DEPOSITION FOR TARGETED DRUG DELIVERY | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2010-03-11 | — | — | WO | disclosed |