Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788781 | 0.81 | ALDH1A1 (0.61) | KDM4CALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27805672 | 0.81 | KEAP1 (0.46) | KDM4CALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4460248 | 0.81 | KDM4E (0.50) | ALDH1A1KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL28641926 | 0.79 | KDM4C (0.41) | KDM4CALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17747457 | 0.78 | GABRP (0.46) | KDM4CALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3789886 | 0.78 | DHODH (0.42) | KDM4CALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30681983 | 0.77 | TSHR (0.45) | ALDH1A1KDM4ECDC7DBF4 | |
| SCHEMBL26617508 | 0.77 | TSHR (0.45) | ALDH1A1KDM4ECDC7DBF4 | |
| SCHEMBL352221 | 0.77 | IKBKB (0.51) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL31133499 | 0.77 | IKBKB (0.51) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010016846-A1 | HETEROCYCLIC MODULATORS OF TGR5 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-02-11 | — | — | WO | disclosed |