Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566575 | 0.86 | PTPN1 (0.44) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3177750 | 0.78 | PTPN1 (0.73) | PTPN1PTPRCPTPN2 | |
| SCHEMBL4566574 | 0.76 | UGT2B7 (0.43) | PTPN1PTPRCPTPN2 | |
| SCHEMBL2691061 | 0.70 | PTPN1 (0.56) | PTPN1PTPRCPTPN2 | |
| SCHEMBL5391873 | 0.70 | NOTUM (0.34) | PTPN1PTPRCPTPN2 | |
| SCHEMBL4563377 | 0.69 | PTPN1 (0.41) | PTPN1PTPRC | |
| SCHEMBL669905 | 0.68 | NOTUM (0.42) | PTPN1PTPN2 | |
| SCHEMBL31337557 | 0.68 | NOTUM (0.42) | PTPN1PTPN2 | |
| SCHEMBL5349984 | 0.67 | CYP1A2 (0.41) | — | |
| SCHEMBL1721014 | 0.67 | CYP1A2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022477-A1 | FUSED AROMATIC PTP-1B INHIBITORS | KANEQ PHARMA INC. (CA) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022477-A1 | FUSED AROMATIC PTP-1B INHIBITORS | PTPRJ, PTPRF, PTPRCAP | PTPN1 14/4885PTPRC 8/4885PTPN2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.