Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410747 | 0.80 | PTPN1 (0.65) | PTPN1PTPRC | |
| SCHEMBL4566575 | 0.77 | PTPN1 (0.44) | PTPN1PTPRC | |
| SCHEMBL4563376 | 0.75 | PTPN1 (0.43) | PTPN1PTPRC | |
| SCHEMBL3264596 | 0.69 | PTPN1 (0.46) | PTPN1PTPRC | |
| SCHEMBL1641368 | 0.66 | BACE1 (0.50) | — | |
| SCHEMBL5473781 | 0.65 | BACE1 (0.54) | — | |
| SCHEMBL4566574 | 0.64 | UGT2B7 (0.43) | PTPN1PTPRC | |
| SCHEMBL14911387 | 0.64 | PDE10A (0.46) | — | |
| SCHEMBL14911775 | 0.63 | PDE10A (0.50) | — | |
| SCHEMBL25422877 | 0.62 | HSD11B1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114971-A1 | FUSED AROMATIC PTP-1B INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008089581-A1 | FUSED AROMATIC PTP-1B INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2008-07-31 | — | — | WO | disclosed |