SCHEMBL3264972

SCHEMBL3264972

CCCC(C)(C)C1=C(C)[SiH](C)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18744472 0.57 CNR2 (0.33)
SCHEMBL12981405 0.56 TSHR (0.50)
SCHEMBL18381788 0.54 CYP19A1 (0.40)
SCHEMBL55485 0.53
SCHEMBL22043129 0.53 ESR1 (0.31)
SCHEMBL20933009 0.53 LMNA (0.35)
SCHEMBL18482107 0.53 APLNR (0.33)
SCHEMBL575234 0.53 TAAR1 (0.56)
SCHEMBL398002 0.53 TAAR1 (0.56)
SCHEMBL18930278 0.53 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3840852-B1 PROCESS FOR THE PRODUCTION OF CANNABINOIDS BESSOR PHARMA LLC (US) 2023-10-04 EP claimed
EP-2382217-B1 NOVEL INTERMEDIATE AND PROCESS FOR PREPARING ENTECAVIR USING SAME HANMI SCIENCE CO LTD (KR) 2013-10-23 EP claimed
EP-0617015-B1 Process for preparing vitamin D3 derivatives and intermediates thereof HOFFMANN LA ROCHE (CH) 1997-10-29 EP claimed
WO-2009140932-A3 METHOD OF PRODUCING (3R,4S)-L-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)- HYDROXYPROPYL)]-4-(4-HYDROXYPHENYL)-2-AZETIDINONE ZENTIVA, K.S. (CZ) 2010-01-14 WO disclosed
WO-2009140932-A2 METHOD OF PRODUCING (3R,4S)-L-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)- HYDROXYPROPYL)]-4-(4-HYDROXYPHENYL)-2-AZETIDINONE ZENTIVA, K.S. (CZ) 2009-11-26 WO disclosed
WO-2001055157-A1 N-SUBSTITUTED DERIVATIVES OF 4-AMINO-4,6-DIDESOXY-α-D-GLUCOPYRANOSYL-(1→4)-α-D-GLUCOPYRANOSYL-(1→4)-D-GLUCOPYRANOSE AND 4-AMINO-4,6-DIDESOXY-α-D-GLUCOPYRANOSYL-(1→4)-α-D-GLUCOPYRANOSYL-(1→4)-β-D-GLUCOPYRANOSIDE AND PREPARATION METHOD CHIRALSEP (FR) 2001-08-02 WO disclosed
EP-0511917-B1 Glycosylated prodrugs, process for their preparation and uses thereof HOECHST SA LAB (FR) 1996-10-23 EP disclosed
WO-1992019639-A1 GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE LABORATOIRES HOECHST (FR) 1992-11-12 WO disclosed
EP-0511917-A1 Glycosylated prodrugs, process for their preparation and uses thereof LABORATOIRES HOECHST S.A. (FR) 1992-11-04 EP disclosed