Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703091 | 0.83 | SIRT6 (0.40) | LCKPARP1SIRT6GABRPGABRD | |
| SCHEMBL29991634 | 0.76 | LCK (0.41) | LCKPARP1SIRT6GABRPGABRD | |
| SCHEMBL22220643 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2PARP1 | |
| SCHEMBL3260502 | 0.70 | PARP1 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2PARP1 | |
| SCHEMBL29935457 | 0.70 | PARP1 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2PARP1 | |
| SCHEMBL30358018 | 0.68 | NNMT (0.39) | LCKKDM4EALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL4950563 | 0.65 | PARP1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2PARP1 | |
| SCHEMBL6360085 | 0.65 | IP6K1 (0.52) | ALDH1A1SMN1; SMN2PARP1CA12CA9 | |
| SCHEMBL6360080 | 0.65 | LCK (0.39) | LCKKDM4EALDH1A1HPGDPARP1 | |
| SCHEMBL28292086 | 0.65 | LCK (0.49) | LCKHPGDPARP1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059552-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |