Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | ACLY | P53396 | 6/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259850 | 0.90 | PPARG (0.43) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL3520754 | 0.82 | PPARG (0.70) | PPARGPPARAPPARDACLY | |
| SCHEMBL3705304 | 0.81 | ACLY (0.47) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL15747081 | 0.80 | ACLY (0.47) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL12804253 | 0.79 | ACLY (0.44) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL3530155 | 0.78 | PPARG (0.55) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL18440703 | 0.77 | PPARG (0.42) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL14653927 | 0.75 | ACLY (0.46) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL6867245 | 0.74 | CA12 (0.54) | PPARGPPARAPPARDHTR6MAPT | |
| SCHEMBL28890855 | 0.73 | NOD1 (0.55) | PPARGPPARAPPARDMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |