SCHEMBL3265609

SCHEMBL3265609

NC(=O)COC(=O)NCCC1CCN(c2cccc(-c3ccccc3)n2)CC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 7/20 0.41
SKP1 P63208 7/20 0.41
SKP2 Q13309 7/20 0.41
CNR1 P21554 1/20 0.41
CHRM4 P08173 6/20 0.40
TGM2 P21980 1/20 0.39
CHRM2 P08172 1/20 0.39
TPSAB1 Q15661 1/20 0.38
TPSD1 Q9BZJ3 1/20 0.38
TPSG1 Q9NRR2 1/20 0.38
HSD11B1 P28845 1/20 0.38
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265618 0.92 CNR1 (0.41) CKS1BSKP1SKP2CNR1CHRM4
SCHEMBL240063 0.90 CKS1B (0.48) CKS1BSKP1SKP2CNR1ACACB
SCHEMBL3268959 0.86 SCD (0.42) CHRM4
SCHEMBL3265574 0.85 TPSAB1 (0.40) CKS1BSKP1SKP2CHRM4CHRM2
SCHEMBL1728924 0.85 CNR1 (0.47) CKS1BSKP1SKP2CNR1CHRM4
SCHEMBL3266883 0.84 CKS1B (0.47) CKS1BSKP1SKP2CNR1HSD11B1
SCHEMBL3265698 0.84 CHRM4 (0.48) CKS1BSKP1SKP2CHRM4CHRM2
SCHEMBL240267 0.82 PDE10A (0.44) ACACBACACA
SCHEMBL3266878 0.82 CKS1B (0.45) CKS1BSKP1SKP2CNR1
SCHEMBL3269876 0.81 HRH3 (0.40) CHRM4TGM2TPSAB1TPSD1TPSG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES SANOFI-AVENTIS (FR) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES CLCN2, CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 CKS1B 1534/4885SKP1 4286/4885SKP2 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.