Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32659841 | 0.94 | ATM (0.37) | NPC1DGAT1ATMMAPTPOLB | |
| SCHEMBL32659866 | 0.88 | MAPT (0.36) | NPC1DGAT1ATMMAPT | |
| SCHEMBL32659868 | 0.83 | NPC1 (0.38) | NPC1MAPTF11 | |
| SCHEMBL32659805 | 0.79 | NPC1 (0.38) | NPC1DGAT1MAPT | |
| SCHEMBL32659846 | 0.78 | NPC1 (0.35) | NPC1MAPT | |
| SCHEMBL32659889 | 0.76 | DGAT1 (0.33) | NPC1DGAT1 | |
| SCHEMBL32659865 | 0.76 | NPC1 (0.33) | NPC1 | |
| SCHEMBL32659847 | 0.74 | DGAT1 (0.35) | NPC1DGAT1MAPTMETAP2 | |
| SCHEMBL32659833 | 0.73 | NPC1 (0.45) | NPC1ATMMAPTPOLBF11 | |
| SCHEMBL32659858 | 0.71 | NPC1 (0.35) | NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |