Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520454 | 0.80 | NPC1 (0.52) | NPC1KDM4EEGFRIGF1RSRC | |
| SCHEMBL32659858 | 0.78 | NPC1 (0.35) | NPC1MAPT | |
| SCHEMBL32659868 | 0.77 | NPC1 (0.38) | NPC1PDE3BPDE3AMAPTF11 | |
| SCHEMBL32659805 | 0.77 | NPC1 (0.38) | NPC1PDE3BPDE3AMAPT | |
| SCHEMBL32659847 | 0.76 | DGAT1 (0.35) | NPC1PDE3BPDE3APDE2AEGFR | |
| SCHEMBL31047155 | 0.75 | NPC1 (0.33) | NPC1MAPTMAPK1 | |
| SCHEMBL31211967 | 0.75 | NPC1 (0.48) | NPC1L3MBTL1POLBTSHR | |
| SCHEMBL32659878 | 0.74 | DGAT1 (0.42) | NPC1PDE3BPDE3AEGFRIGF1R | |
| SCHEMBL27395347 | 0.72 | NPC1 (0.41) | NPC1MAPTPDE10AF11TSHR | |
| SCHEMBL30771170 | 0.71 | NPC1 (0.45) | NPC1EGFRIGF1RSRCFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |