SCHEMBL32660033

SCHEMBL32660033

O=C(c1ccc(Cl)c([N+](=O)[O-])c1)N1CCOCC1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.72
SMN1; SMN2 Q16637 4/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 2/20 0.68
PKM P14618 1/20 0.68
MAPT P10636 1/20 0.67
HPGD P15428 1/20 0.60
VCAM1 P19320 1/20 0.57
LMNA P02545 2/20 0.57
NPC1 O15118 1/20 0.57
HTT P42858 1/20 0.57
RAB9A P51151 1/20 0.57
PHGDH O43175 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546063 0.87 ALDH1A1 (0.78) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL5754852 0.86 L3MBTL1 (0.69) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL32659997 0.85 L3MBTL1 (0.65) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL32660003 0.84 L3MBTL1 (0.70) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL22767195 0.84 GAA (1.00) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL30501408 0.84 GAA (0.72) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL11287512 0.84 GAA (0.72) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL20597980 0.84 GAA (0.72) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL3638856 0.83 GAA (0.70) GAASMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL7671473 0.83 SMN1; SMN2 (0.79) GAASMN1; SMN2MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678633-A1 NOVEL FERROPTOSIS INHIBITORS Universiteit Antwerpen (BE) 2026-01-14 EP disclosed