Chalcone

Chalcone

SCHEMBL3266057

C(OCC1CO1)C1CO1.O=C(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.61
CYP1B1 Q16678 7/20 0.61
MAOB P27338 6/20 0.61
LMNA P02545 3/20 0.61
BCHE P06276 2/20 0.61
TNFRSF1A P19438 2/20 0.61
PLIN1 O60240 1/20 0.61
ACHE P22303 1/20 0.61
RECQL P46063 1/20 0.61
PLIN5 Q00G26 1/20 0.61
ABHD5 Q8WTS1 1/20 0.61
MGLL Q99685 1/20 0.55
KMT2A Q03164 5/20 0.51
CYP3A4 P08684 4/20 0.51
RAB9A P51151 4/20 0.51
HSPD1 P10809 3/20 0.51
HSPE1 P61604 3/20 0.51
MEN1 O00255 3/20 0.51
NFKB1 P19838 2/20 0.51
NFKB2 Q00653 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chalcone SCHEMBL3266054 1.00 MAPT (0.61) MAPTCYP1B1MAOBLMNABCHE
SCHEMBL10631340 0.87 MGLL (0.59) MAPTLMNABCHEPLIN1RECQL
Chalcone SCHEMBL28747849 0.86 CYP1B1 (0.65) MAPTCYP1B1MAOBLMNABCHE
SCHEMBL12285237 0.84 MGLL (0.60) MAPTCYP1B1MAOBLMNABCHE
SCHEMBL30789056 0.82 MAOB (0.60) MAPTCYP1B1MAOBLMNABCHE
SCHEMBL27165212 0.82 MAOB (0.60) MAPTCYP1B1MAOBLMNABCHE
SCHEMBL9077728 0.81 MAPT (0.57) MAPTCYP1B1MAOBLMNABCHE
Benzoic Acid SCHEMBL283023 0.79 DAO (0.50) MGLLTDP1ALDH1A1
Benzophenone SCHEMBL27841911 0.79 TDP1 (0.50) MGLLTDP1ALDH1A1L3MBTL1
Benzil SCHEMBL13571700 0.79 CES2 (0.50) MGLLTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112292435-B Sealant composition, sealing sheet, and sealing body 琳得科株式会社 2023-09-01 CN disclosed
CN-112292435-A Sealing agent composition, sealing sheet, and sealing body 琳得科株式会社 2021-01-29 CN disclosed
CN-101945946-B Flame-retardant resin composition and coated electric wire WINTECH POLYMER LTD 2013-02-13 CN disclosed
CN-101945946-A Flame-retardant resin composition and coated electric wire WINTECH POLYMER LTD 2011-01-12 CN disclosed
EP-1449882-B1 IMPACT-RESISTANT CYCLIC OLEFIN BASED RESIN COMPOSITION AND MOLDINGS POLYPLASTICS CO (JP) 2010-06-02 EP disclosed
US-7612131-B2 Flame-retardant resin composition WINTECH POLYMER LTD. (JP) 2009-11-03 US disclosed
US-20080167406-A1 FLAME-RETARDANT RESIN COMPOSITION WINTECH POLYMER, LTD. (JP) 2008-07-10 US disclosed
EP-1935944-A2 Flame-retardant resin composition Wintech Polymer Ltd. (JP) 2008-06-25 EP disclosed
CN-1323114-C Polyarylene sulfide resin composition and molded product thereof POLYPLASTICS CO (JP) 2007-06-27 CN disclosed
CN-1320059-C Amorphous wholly aromatic polyester amide composition POLYPLASTICS CO (JP) 2007-06-06 CN disclosed
CN-1142235-A Modified polyacetal and process for production thereof POLYPLASTICS CO (JP) 1997-02-05 CN disclosed
US-5349007-A With olefin polymers POLYPLASTICS CO., LTD. (JP) 1994-09-20 US disclosed
US-5254609-A Impact strength, heat resistance POLYPLASTICS CO., LTD. (JP) 1993-10-19 US disclosed
US-5242959-A Blends POLYPLASTICS CO., LTD. (JP) 1993-09-07 US disclosed
US-5227427-A Blending with polyolefin and unsaturated epoxy monomer POLYPLASTICS CO., LTD. (JP) 1993-07-13 US disclosed
US-5218043-A Blend of polyarylene sulfide, polyester, n-(4-(2,3-epxoypropyxy)-3,5-dimethyl-benzyl) acrylamide coupler, a polymeration catalyst and a filler POLYPLASTICS CO., LTD. (JP) 1993-06-08 US disclosed
EP-0495643-A2 Polyarylene sulphide resin composition and process for producing the same POLYPLASTICS CO. LTD. (JP) 1992-07-22 EP disclosed
EP-0492949-A2 Polyarylene sulfide resin composition and process for the preparation of the same POLYPLASTICS CO. LTD. (JP) 1992-07-01 EP disclosed
EP-0492976-A2 Polyester resin composition and process for producing the same POLYPLASTICS CO. LTD. (JP) 1992-07-01 EP disclosed
EP-0491535-A2 Polyarylene sulfide resin composition excellent in adhesion and process for the preparation of the same POLYPLASTICS CO. LTD. (JP) 1992-06-24 EP disclosed