SCHEMBL9077728

SCHEMBL9077728

O=C(C=Cc1ccc(CC2CO2)cc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.57
MAOB P27338 3/20 0.57
LMNA P02545 3/20 0.57
BCHE P06276 3/20 0.57
PLIN1 O60240 1/20 0.57
TNFRSF1A P19438 1/20 0.57
ACHE P22303 1/20 0.57
RECQL P46063 1/20 0.57
PLIN5 Q00G26 1/20 0.57
CYP1B1 Q16678 1/20 0.57
ABHD5 Q8WTS1 1/20 0.57
RAB9A P51151 6/20 0.55
KMT2A Q03164 4/20 0.55
CYP3A4 P08684 3/20 0.55
NFKB1 P19838 2/20 0.55
NFKB2 Q00653 2/20 0.55
RELA Q04206 2/20 0.55
HSPD1 P10809 1/20 0.55
PKM P14618 1/20 0.55
HSPE1 P61604 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1774352 0.84 HCAR2 (0.49) MAPTLMNAKMT2ACYP3A4NFKB1
Chalcone SCHEMBL28747849 0.83 CYP1B1 (0.65) MAPTMAOBLMNABCHEPLIN1
Chalcone SCHEMBL3266057 0.81 MAPT (0.61) MAPTMAOBLMNABCHEPLIN1
Chalcone SCHEMBL3266054 0.81 MAPT (0.61) MAPTMAOBLMNABCHEPLIN1
SCHEMBL12285237 0.79 MGLL (0.60) MAPTMAOBLMNABCHEPLIN1
SCHEMBL8431772 0.78 CYP1B1 (0.91) MAPTMAOBLMNABCHEPLIN1
SCHEMBL9915665 0.78 CYP1B1 (0.91) MAPTMAOBLMNABCHEPLIN1
SCHEMBL3194434 0.78 MAPT (0.47) MAPTMAOBLMNABCHEPLIN1
SCHEMBL3194425 0.78 MAPT (0.47) MAPTMAOBLMNABCHEPLIN1
SCHEMBL25232470 0.77 MAPT (0.70) MAPTMAOBLMNABCHEPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed