SCHEMBL3266102

SCHEMBL3266102

Nc1ccc2c(c1CCO)C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.57
MAOB P27338 1/20 0.57
ADORA2A P29274 5/20 0.52
CSNK1A1 P48729 2/20 0.52
CSNK1D P48730 2/20 0.52
CSNK1G1 Q9HCP0 2/20 0.52
FGR P09769 1/20 0.52
PIM1 P11309 1/20 0.52
DYRK1A Q13627 1/20 0.52
HIPK2 Q9H2X6 1/20 0.52
MEN1 O00255 9/20 0.50
KMT2A Q03164 9/20 0.50
ALDH1A1 P00352 8/20 0.50
POLB P06746 7/20 0.50
MAPK1 P28482 7/20 0.50
MAPT P10636 7/20 0.50
MCL1 Q07820 4/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
THRB P10828 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11263052 0.83 MAOA (0.56) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL2315928 0.82 ELANE (0.49) MAOAMAOBADORA2AMEN1KMT2A
Hydrochloric Acid SCHEMBL8701117 0.80 MAOA (0.53) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL11792659 0.80 MAOA (0.53) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL16145028 0.77 ALDH1A1 (0.58) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL9355397 0.76 MAOA (0.56) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL397172 0.74 MEN1 (0.67) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL31026205 0.74 MEN1 (0.67) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL487001 0.73 MAOA (1.00) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL30129869 0.73 MAOA (1.00) MAOAMAOBADORA2ACSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1456598-A Organic pigments with superbranched polymers as cores and preparations thereof UNIV SHANGHAI COMMUNICATION (CN) 2003-11-19 CN claimed
EP-1302560-B1 SILICON OXIDE MEMBRANE TOYO SEIKAN KAISHA LTD (JP) 2010-06-02 EP disclosed
US-6818310-B2 SILICON OXIDE ON PLASTIC; SHUTOFF VALVE TOYO SEIKAN KAISHA, LTD. (JP) 2004-11-16 US disclosed
CN-1456598-A Organic pigments with superbranched polymers as cores and preparations thereof UNIV SHANGHAI COMMUNICATION (CN) 2003-11-19 CN disclosed
US-20030165696-A1 Silicon oxide membrane TOYO SEIKAN KAISHA, LTD. (JP) 2003-09-04 US disclosed
EP-1302560-A1 SILICON OXIDE MEMBRANE TOYO SEIKAN KAISHA, LTD. (JP) 2003-04-16 EP disclosed