SCHEMBL9355397

SCHEMBL9355397

C=CCc1c(N)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
MAOB P27338 1/20 0.56
ADORA2A P29274 5/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
FGR P09769 1/20 0.50
PIM1 P11309 1/20 0.50
DYRK1A Q13627 1/20 0.50
HIPK2 Q9H2X6 1/20 0.50
MEN1 O00255 9/20 0.45
KMT2A Q03164 9/20 0.45
ALDH1A1 P00352 8/20 0.45
POLB P06746 7/20 0.45
MAPK1 P28482 6/20 0.45
MAPT P10636 6/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
MCL1 Q07820 4/20 0.45
TDP1 Q9NUW8 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063387 0.87 ELANE (0.41) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL728511 0.85 ELANE (0.46) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL7600157 0.83 ELANE (0.48) MAOAMAOBADORA2AMEN1KMT2A
SCHEMBL28848100 0.80 ELANE (0.46) MAOAMAOBADORA2AMEN1KMT2A
SCHEMBL5420921 0.79 ADORA2A (0.43) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL9282673 0.78 MAOA (0.56) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL3266102 0.76 MAOA (0.57) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL8653935 0.76 MAOA (0.53) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL11263052 0.75 MAOA (0.56) MAOAMAOBADORA2ACSNK1A1CSNK1D
SCHEMBL175397 0.73 GABRA1 (0.50) MAOAMAOBADORA2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368750-B1 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL CO (JP) 1994-10-26 EP disclosed
US-5017713-A Alkylation SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-05-21 US disclosed
EP-0368750-A2 Process for preparing substituted aminoanthraquinones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed