SCHEMBL32661391

SCHEMBL32661391

CCOC(=O)C(CC)C1CC(C2CCCCCC2)CN(Cc2ccc(C(F)(F)F)cc2)C1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ KCNH2 Q12809 5/20 0.39
▸ CACNA1B Q00975 1/20 0.39
▸ DNMT1 P26358 1/20 0.39
▸ EHMT2 Q96KQ7 1/20 0.39
▸ ADRB2 P07550 1/20 0.39
▸ HRH3 Q9Y5N1 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ GPR119 Q8TDV5 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ PTGDR2 Q9Y5Y4 1/20 0.38
▸ PHGDH O43175 1/20 0.38
▸ TEAD1 P28347 2/20 0.38
▸ EPHX2 P34913 1/20 0.38
▸ PPARG P37231 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32661153 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL32661396 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL32661277 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL32661370 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL32661494 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL32661179 0.82 ALDH1A1 (0.49) KDM4EALDH1A1KCNH2ADRB2HRH3
SCHEMBL29087753 0.77 HIF1A (0.41) KDM4EALDH1A1DNMT1EHMT2L3MBTL1
SCHEMBL29087751 0.77 HIF1A (0.41) KDM4EALDH1A1DNMT1EHMT2L3MBTL1
SCHEMBL32661400 0.74 KDM4E (0.45) KDM4EALDH1A1KCNH2HRH3TEAD1
SCHEMBL32661252 0.74 KDM4E (0.45) KDM4EALDH1A1KCNH2HRH3TEAD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015323-A1 PIPERIDINE COMPOUNDS TELO THERAPEUTICS INC (US) 2026-01-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015323-A1 PIPERIDINE COMPOUNDS XPO1, NR0B1, NR2E1 KDM4E 3383/4885ALDH1A1 1959/4885KCNH2 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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