Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087751 | 1.00 | HIF1A (0.41) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29087693 | 0.89 | HIF1A (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29087696 | 0.89 | HIF1A (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29617617 | 0.88 | L3MBTL1 (0.47) | HIF1AEPAS1L3MBTL1CYP3A4KDM4E | |
| SCHEMBL29617642 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL29617606 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL27136637 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL26970080 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL32661391 | 0.77 | KDM4E (0.48) | DNMT1EHMT2L3MBTL1CYP3A4KDM4E | |
| SCHEMBL29617620 | 0.77 | KDM4E (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416202-A1 | Small Molecule Compounds and Compositions | TELO THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416202-A1 | Small Molecule Compounds and Compositions | TERT, TP53, EP300 | HIF1A 2084/4885EPAS1 589/4885DNMT1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.