Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087753 | 1.00 | HIF1A (0.41) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29087693 | 0.89 | HIF1A (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29087696 | 0.89 | HIF1A (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 | |
| SCHEMBL29617617 | 0.88 | L3MBTL1 (0.47) | HIF1AEPAS1L3MBTL1CYP3A4KDM4E | |
| SCHEMBL29617642 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL29617606 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL27136637 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL26970080 | 0.80 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4ETEAD1 | |
| SCHEMBL32661391 | 0.77 | KDM4E (0.48) | DNMT1EHMT2L3MBTL1CYP3A4KDM4E | |
| SCHEMBL29617620 | 0.77 | KDM4E (0.43) | HIF1AEPAS1DNMT1EHMT2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |