Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251459 | 0.90 | — | — | |
| Putrescine SCHEMBL17041947 | 0.90 | NFKB1 (0.63) | NFKB1CYP2D6KMT2ALMNABLM | |
| Succinamide SCHEMBL11042748 | 0.89 | BLM (0.41) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL17041943 | 0.89 | NFKB1 (0.45) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL125606 | 0.89 | KMT2A (0.48) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL728964 | 0.87 | LMNA (0.65) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL601687 | 0.87 | LMNA (0.65) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL4964830 | 0.87 | LMNA (0.65) | NFKB1CYP2D6KMT2ALMNABLM | |
| SCHEMBL285471 | 0.87 | — | — | |
| SCHEMBL9423045 | 0.87 | LMNA (0.65) | NFKB1CYP2D6KMT2ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024106504-A1 | VAPOR DEPOSITION FILM, MULTILAYER STRUCTURE, PACKAGING MATERIAL, VACUUM PACKAGING BAG AND VACUUM THERMAL INSULATION BODY | 株式会社クラレ | 2024-05-23 | — | — | WO | disclosed |
| WO-2024071139-A1 | MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME, AUTOMOBILE PART, AIRCRAFT PART, AND DAMPING MATERIAL FOR CARBON-FIBER-REINFORCED PLASTIC | 三菱ケミカル株式会社 | 2024-04-04 | — | — | WO | disclosed |
| EP-4339241-A1 | COMPATIBILIZER, RECYCLING AID, AND COMPATIBILIZATION METHOD | MCPP Innovation LLC (JP) | 2024-03-20 | — | — | EP | disclosed |
| EP-4339242-A1 | POLYMER COMPOSITION AND MOLDED ARTICLE THEREOF | Mitsubishi Chemical Corporation (JP) | 2024-03-20 | — | — | EP | disclosed |
| US-20240059814-A1 | COMPATIBILIZER, RECYCLING AGENT, AND COMPATIBILIZATION METHOD | MCPP INNOVATION LLC (JP) | 2024-02-22 | — | — | US | disclosed |
| US-20240042657-A1 | POLYMER COMPOSITION AND MOLDED ARTICLE THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-3395892-B1 | RESIN COMPOSITION AND MULTILAYER STRUCTURE USING SAME | MITSUBISHI CHEM CORP (JP) | 2024-01-10 | — | — | EP | disclosed |
| WO-2023139987-A1 | PARTICLES AND USE THEREOF | 松本油脂製薬株式会社 | 2023-07-27 | — | — | WO | disclosed |
| US-11667761-B2 | Ethylene-vinyl alcohol copolymer composition pellet and process for producing said ethylene-vinyl alcohol copolymer composition pellet | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-06-06 | — | — | US | disclosed |
| WO-2023054541-A1 | METHOD FOR RECOVERING CYCLIC OLEFIN RESIN | グンゼ株式会社 | 2023-04-06 | — | — | WO | disclosed |
| EP-1043361-A1 | Resin composition and laminate | Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5939205-A | COMPRISING INORGANIC VAPOR DEPOSITED LAYER AND A POLYIMIDE FILM HAVING ANCHOR COAT LAYER ON AT LEAST ONE SIDE; WRAPPINGMATERIAL FOR FOODS, DRUGS, MEDICAL PRODUCTS, ELECTRONICS | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0331072-B1 | Multilayered container | KURARAY CO (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0806448-A2 | Gas barrier resin film | Toyo Boseki Kabushiki Kaisha (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0400604-B1 | Multilayered structure | KURARAY CO (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5094921-A | Thermoplastic, ethylene-vinyl acetate, gas barrier packaging | KURARAY CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0400604-A2 | Multilayered structure | KURARAY CO., LTD. (JP) | 1990-12-05 | — | — | EP | disclosed |
| EP-0176229-B1 | MULTI-LAYER GAS-BARRIER DRAWN POLYESTER VESSEL | TOYO SEIKAN KAISHA LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4816304-A | ETHYLENE-VINYL ALCOHOL BARRIER AND POLYAMIDE ADHESIVE | TOYO SEIKAN KAISHA, LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0176229-A1 | Multi-layer gas-barrier drawn polyester vessel | TOYO SEIKAN KAISHA LIMITED (JP) | 1986-04-02 | — | — | EP | disclosed |