Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20477246 | 0.82 | CYP19A1 (0.54) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24709861 | 0.79 | MEN1 (0.47) | MAPTLMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL32663501 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2USP2CYP3A4MAPTLMNA | |
| SCHEMBL7613 | 0.76 | ALDH1A1 (0.57) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL12373440 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2USP2CYP3A4MAPTLMNA | |
| SCHEMBL29952019 | 0.73 | ELANE (0.44) | SMN1; SMN2MAPTALDH1A1KDM4EELANE | |
| SCHEMBL29956715 | 0.73 | ELANE (0.46) | SMN1; SMN2MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL4693433 | 0.72 | PDE4B (0.55) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29955892 | 0.72 | ELANE (0.45) | SMN1; SMN2USP2CYP3A4MAPTLMNA | |
| SCHEMBL26783067 | 0.72 | PDE4D (0.41) | SMN1; SMN2PDE4DUSP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680608-A1 | 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS | MMV Medicines for Malaria Venture (CH) | 2026-01-21 | — | — | EP | disclosed |