Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22438753 | 0.76 | RXFP1 (0.53) | ELANEF2PLAUALDH1A1MAPT | |
| SCHEMBL29956715 | 0.75 | ELANE (0.46) | ELANEALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7613 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL29955892 | 0.74 | ELANE (0.45) | ELANEALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL32663296 | 0.73 | SMN1; SMN2 (0.42) | ELANEALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL20477246 | 0.73 | CYP19A1 (0.54) | ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL24709861 | 0.73 | MEN1 (0.47) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16517612 | 0.72 | ALDH1A1 (0.48) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL29955507 | 0.72 | SPR (0.40) | ELANEF2PLAUALDH1A1MAPT | |
| SCHEMBL31277480 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |