Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955892 | 0.81 | ELANE (0.45) | ELANEMAPTSMN1; SMN2ALDH1A1TARBP2 | |
| SCHEMBL30710766 | 0.80 | CYP19A1 (0.49) | ELANEMAPTSMN1; SMN2TARBP2LMNA | |
| SCHEMBL25150416 | 0.76 | HTT (0.50) | ELANEMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29952019 | 0.75 | ELANE (0.44) | ELANEMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29955507 | 0.74 | SPR (0.40) | ELANEMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL23360824 | 0.74 | ELANE (0.46) | ELANEMAPTALDH1A1TARBP2LMNA | |
| SCHEMBL32663296 | 0.73 | SMN1; SMN2 (0.42) | ELANEMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2288847 | 0.71 | LMNA (0.49) | MAPTSMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL20477246 | 0.71 | CYP19A1 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNACYP19A1 | |
| SCHEMBL7613 | 0.70 | ALDH1A1 (0.57) | MAPTALDH1A1RAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |