SCHEMBL3266348

SCHEMBL3266348

CC(F)C(F)(OCc1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
TSHR P16473 3/20 0.38
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
CA1 P00915 1/20 0.37
KMT2A Q03164 1/20 0.36
TACR1 P25103 2/20 0.35
IDO1 P14902 1/20 0.35
ALDH1A1 P00352 2/20 0.34
AGXT P21549 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328694 0.73 TSHR (0.35) PTPN1TSHRHTR2AHTR2CHTR2B
SCHEMBL9172757 0.73 TSHR (0.41) PTPN1TSHRCA1IDO1ALDH1A1
SCHEMBL8963799 0.71 ALDH1A1 (0.42) PTPN1TSHRCA1KMT2AALDH1A1
SCHEMBL3434137 0.71 TSHR (0.48) PTPN1TSHRKMT2ATACR1IDO1
SCHEMBL2345113 0.71 TSHR (0.33) PTPN1TSHRHTR2AHTR2CHTR2B
SCHEMBL267071 0.71 TSHR (0.52) PTPN1TSHRCA1KMT2AIDO1
SCHEMBL19388050 0.71 RORC (0.53) PTPN1TSHRIDO1ALDH1A1
SCHEMBL20644255 0.70 TACR1 (0.42) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL19451402 0.70 TACR1 (0.42) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL7723437 0.70 TSHR (0.46) PTPN1TSHRCA1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192087-A1 ALKALI METAL FLUORIDE DISPERSION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed