Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5547174 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL3059784 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL29088008 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL5134179 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL5541245 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL6385117 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| SCHEMBL23141152 | 0.97 | PLA2G1B (0.62) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| SCHEMBL20746344 | 0.97 | PLA2G1B (0.62) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| SCHEMBL11289661 | 0.97 | PLA2G1B (0.62) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| SCHEMBL20746346 | 0.97 | PLA2G1B (0.62) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070212403-A1 | Method for Selecting Cationic or Anionic Liposomes for Treatment of a Mucosa Membrane, and Kit Comprising the Same | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-09-13 | — | — | US | claimed |
| EP-1694298-A2 | METHOD FOR SELECTING CATIONIC OR ANIONIC LIPOSOMES FOR TREATMENT OF A MUCOSA MEMBRANE, AND KIT COMPRISING THE SAME | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2006-08-30 | — | — | EP | claimed |
| WO-2005041932-A2 | METHOD FOR SELECTING CATIONIC OR ANIONIC LIPOSOMES FOR TREATMENT OF A MUCOSA MEMBRANE, AND KIT COMPRISING THE SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-05-12 | — | — | WO | claimed |
| US-12635710-B2 | Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions | EASTMAN CHEMICAL COMPANY (US) | 2026-05-26 | — | — | US | disclosed |
| US-20250320388-A1 | WATERBORNE ADHESIVE AND/OR SEALANT COMPOSITION | SOUDAL (BE) | 2025-10-16 | — | — | US | disclosed |
| EP-4291157-B1 | FRAGRANCE DELIVERY COMPOSITIONS | TAMINCO BV (BE) | 2025-03-19 | — | — | EP | disclosed |
| WO-2024246352-A1 | WATERBORNE CURABLE SEALANT COMPOSITION | SOUDAL (BE) | 2024-12-05 | — | — | WO | disclosed |
| EP-4081034-B1 | METHOD FOR GROWING PLANTS | TAMINCO BV (BE) | 2024-10-23 | — | — | EP | disclosed |
| EP-4437060-A1 | WATERBORNE ADHESIVE AND/OR SEALANT COMPOSITION | Soudal (BE) | 2024-10-02 | — | — | EP | disclosed |
| US-20240215608-A1 | METHODS OF USING FORMALDEHYDE-FREE ANTIMICROBIAL COMPOSITIONS IN ANIMAL BY-PRODUCT COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240148630-A1 | FRAGRANCE DELIVERY COMPOSITIONS | TAMINCO BV (BE) | 2024-05-09 | — | — | US | disclosed |
| CN-105189531-B | Peptides for skin rejuvenation and methods of use thereof | 安特易斯有限公司 | 2020-02-21 | — | — | CN | disclosed |
| US-10061151-B2 | Light shielding material and display device including the same | LG DISPLAY CO., LTD. (KR) | 2018-08-28 | — | — | US | disclosed |
| US-20180069235-A1 | ANODE ACTIVE MATERIAL FOR SECONDARY BATTERY AND PREPARATION METHOD THEREOF | GS ENERGY CORP. (KR) | 2018-03-08 | — | — | US | disclosed |
| WO-2017147407-A1 | COMPOSITIONS COMPRISING COMPOSITE NANOCARRIERS AND METHODS OF MAKING AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20150378182-A1 | LIGHT SHIELDING MATERIAL AND DISPLAY DEVICE INCLUDING THE SAME | LG DISPLAY CO., LTD. (KR) | 2015-12-31 | — | — | US | disclosed |
| EP-1694298-B1 | METHOD FOR SELECTING CATIONIC OR ANIONIC LIPOSOMES FOR TREATMENT OF A MUCOSA MEMBRANE, AND KIT COMPRISING THE SAME | YISSUM RES DEV CO (IL) | 2010-06-09 | — | — | EP | disclosed |
| US-20070233024-A1 | Sanitary Thin Paper and Process for Producing the Same | DAIO PAPER CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-20070212403-A1 | Method for Selecting Cationic or Anionic Liposomes for Treatment of a Mucosa Membrane, and Kit Comprising the Same | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-09-13 | — | — | US | disclosed |
| EP-1752580-A1 | SANITARY THIN PAPER AND PROCESS FOR PRODUCING THE SAME | Daio Paper Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12635710-B2 | Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions | FABP2, FABP1, VIP | PLA2G1B 908/4885PLA2G2A 1381/4885S1PR2 3861/4885 |
| US-20240148630-A1 | FRAGRANCE DELIVERY COMPOSITIONS | F12, P4HA1, INO80C | PLA2G1B 4166/4885PLA2G2A 4823/4885S1PR2 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.