Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665189 | 0.90 | MAP4K4 (0.45) | ADH5KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL32664946 | 0.88 | SLC2A1 (0.47) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL32664938 | 0.88 | MEN1 (0.45) | ADH5KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL32664937 | 0.87 | RXRA (0.47) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL32665006 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL32665023 | 0.81 | KMO (0.45) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL32665408 | 0.80 | CAMK2D (0.44) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL32665047 | 0.80 | MAPT (0.43) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL32664923 | 0.80 | CAMK2D (0.42) | ALDH1A1KDM5B | |
| SCHEMBL32665240 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV MINNESOTA (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | NR5A1, CYP17A1, CNR1 | ADH5 446/4885KDM4E 1972/4885ALDH1A1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.