Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.58 |
| ▸ | TERT | O14746 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412018 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1EGLN2TERTNAMPT | |
| SCHEMBL23484191 | 0.89 | KDM4E (0.69) | KDM4EALDH1A1EGLN2NAMPTPARP1 | |
| SCHEMBL285298 | 0.89 | SMN1; SMN2 (0.62) | KDM4EALDH1A1TERTCYP1A2TSHR | |
| SCHEMBL9667962 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1EGLN2NAMPTPARP1 | |
| SCHEMBL15504664 | 0.84 | SMN1; SMN2 (0.57) | KDM4EALDH1A1TERTCYP1A2TSHR | |
| SCHEMBL9447586 | 0.84 | GRIN1 (0.62) | KDM4EALDH1A1EGLN2NAMPTSMN1; SMN2 | |
| SCHEMBL163436 | 0.83 | L3MBTL1 (0.71) | KDM4EALDH1A1EGLN2NAMPTMEN1 | |
| SCHEMBL10123874 | 0.83 | TERT (0.55) | KDM4EALDH1A1TERTCYP1A2TSHR | |
| SCHEMBL7880194 | 0.83 | KDM4E (0.70) | KDM4ETERTCYP1A2TSHRNFKB1 | |
| SCHEMBL3197946 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1EGLN2NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KDM4E 3880/4885ALDH1A1 3714/4885EGLN2 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.