SCHEMBL3197946

SCHEMBL3197946

O=C(O)CCNC(=O)c1cccc(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
ALDH1A1 P00352 3/20 0.59
EGLN2 Q96KS0 1/20 0.56
ITGB3 P05106 2/20 0.56
ITGA2B P08514 1/20 0.56
LMNA P02545 1/20 0.55
NAMPT P43490 1/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA12 O43570 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
PRSS1 P07477 1/20 0.50
CTSG P08311 1/20 0.50
CTRB1 P17538 1/20 0.50
CMA1 P23946 1/20 0.50
HPGD P15428 1/20 0.50
HPGDS O60760 1/20 0.49
ITGA2 P17301 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717417 0.90 ITGB3 (0.65) ITGB3ITGA2BLMNACA1CA2
SCHEMBL30481056 0.88 LMNA (0.72) KDM4EALDH1A1LMNANAMPTSMN1; SMN2
SCHEMBL5657986 0.88 LMNA (0.72) KDM4EALDH1A1LMNANAMPTSMN1; SMN2
SCHEMBL23484191 0.88 KDM4E (0.69) KDM4EALDH1A1EGLN2LMNANAMPT
SCHEMBL13313834 0.85 KDM4E (0.57) KDM4EALDH1A1EGLN2NAMPTCA1
SCHEMBL600772 0.83 KDM4E (0.62) KDM4EALDH1A1EGLN2LMNANAMPT
SCHEMBL9667962 0.83 KDM4E (0.62) KDM4EALDH1A1EGLN2NAMPTCA1
SCHEMBL29395845 0.83 KDM4E (0.62) KDM4EALDH1A1EGLN2LMNANAMPT
Betamipron SCHEMBL4498475 0.82 PRSS1 (0.70) LMNACA1CA2SMN1; SMN2PRSS1
Betamipron SCHEMBL605899 0.82 PRSS1 (0.70) LMNACA1CA2SMN1; SMN2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619000-A1 PHOSPHORUS-CONTAINING COMPOUNDS FOR TREATING INFLAMMATORY BOWEL DIESEASE Vivavision Biotech, Inc. (CN) 2025-09-24 EP claimed
WO-2024104422-A1 PHOSPHORUS-CONTAINING COMPOUNDS FOR TREATING INFLAMMATORY BOWEL DIESEASE VIVAVISION BIOTECH, INC. (CN) 2024-05-23 WO claimed
EP-4619000-A1 PHOSPHORUS-CONTAINING COMPOUNDS FOR TREATING INFLAMMATORY BOWEL DIESEASE Vivavision Biotech, Inc. (CN) 2025-09-24 EP disclosed
WO-2024104422-A1 PHOSPHORUS-CONTAINING COMPOUNDS FOR TREATING INFLAMMATORY BOWEL DIESEASE VIVAVISION BIOTECH, INC. (CN) 2024-05-23 WO disclosed
US-8937090-B2 Parakeratosis inhibitor, pore-shrinking agent and external composition for skin SHISEIDO COMPANY, LTD. (JP) 2015-01-20 US disclosed
US-20120232111-A1 Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin SHISEIDO COMPANY, LTD. (JP) 2012-09-13 US disclosed
US-20120165409-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20100035881-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2010-02-11 US disclosed
EP-1941861-A1 WRINKLE-IMPROVING AGENT Shiseido Company, Limited (JP) 2008-07-09 EP disclosed
EP-1880711-A1 PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN Shiseido Company, Limited (JP) 2008-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035881-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 KDM4E 4157/4885ALDH1A1 1501/4885EGLN2 3093/4885
US-20120232111-A1 Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin CUTA, AAAS, NUP160 KDM4E 3885/4885ALDH1A1 3543/4885EGLN2 2434/4885
US-20120165409-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 KDM4E 4258/4885ALDH1A1 1151/4885EGLN2 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.