Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665176 | 0.92 | STS (0.36) | HTR1ACYP3A4ALDH1A1KDM4EHPGD | |
| SCHEMBL32665523 | 0.85 | CYP2D6 (0.41) | CYP3A4ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL32665186 | 0.83 | MAPK1 (0.41) | CYP3A4ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL32665432 | 0.79 | NPSR1 (0.36) | ALDH1A1MEN1KMT2ADRD2 | |
| SCHEMBL32665089 | 0.73 | DOCK5 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL32665268 | 0.69 | CYP2C9 (0.33) | CYP3A4ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL32665454 | 0.69 | FFAR4 (0.38) | HTR1ACYP3A4ALDH1A1HPGDTSHR | |
| SCHEMBL32665034 | 0.69 | L3MBTL3 (0.46) | ALDH1A1KDM4EMEN1KMT2AMGLL | |
| SCHEMBL2762664 | 0.66 | MAPK1 (0.62) | HTR1ACYP3A4ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL2763425 | 0.66 | MAPK1 (0.60) | HTR1ACYP3A4ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | HTR1A 4144/4885CYP3A4 4706/4885ALDH1A1 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.