Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665186 | 0.86 | MAPK1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL32665434 | 0.81 | NPC1 (0.51) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL32665285 | 0.80 | ALDH1A1 (0.36) | L3MBTL3L3MBTL1ALDH1A1MGLL | |
| Hydrochloric Acid SCHEMBL32665008 | 0.80 | KMT2A (0.47) | L3MBTL1HSD11B1ALDH1A1MGLLMEN1 | |
| SCHEMBL32665569 | 0.76 | OPRM1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL32665174 | 0.76 | NOTUM (0.40) | L3MBTL3L3MBTL1ALDH1A1MGLL | |
| SCHEMBL32665450 | 0.76 | NOTUM (0.40) | L3MBTL3L3MBTL1ALDH1A1MGLL | |
| SCHEMBL32665520 | 0.74 | GFER (0.48) | HSD11B1ALDH1A1MGLLKMT2ACACNA1B | |
| Formic Acid SCHEMBL32665547 | 0.74 | OPRM1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL32665143 | 0.71 | L3MBTL3 (0.37) | L3MBTL3L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | L3MBTL3 1350/4885L3MBTL1 675/4885HSD11B1 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.