Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665440 | 0.80 | KMT2A (0.45) | CES2CES1BCHEALBTSHR | |
| SCHEMBL32665556 | 0.79 | PTPN1 (0.41) | PTPN1CES2CES1BCHEKAT6A | |
| SCHEMBL32665331 | 0.76 | ELANE (0.47) | PTPN1HPGDSGSK3BALDH1A1 | |
| SCHEMBL26664898 | 0.76 | ELANE (0.42) | CES2CES1BCHEEPAS1SLC2A1 | |
| SCHEMBL32665111 | 0.74 | KMT2A (0.40) | ALDH1A1 | |
| SCHEMBL1743414 | 0.73 | CES2 (0.61) | PTPN1CES2CES1BCHEKAT6A | |
| SCHEMBL30956741 | 0.73 | CES2 (0.61) | PTPN1CES2CES1BCHEKAT6A | |
| SCHEMBL29844777 | 0.73 | PTPN1 (0.58) | PTPN1CES2CES1BCHEKAT6A | |
| SCHEMBL166429 | 0.73 | PTPN1 (0.58) | PTPN1CES2CES1BCHEKAT6A | |
| SCHEMBL31298304 | 0.72 | PTPN1 (0.50) | PTPN1CES2CES1BCHEKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | PTPN1 4150/4885CES2 2979/4885CES1 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.