Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665556 | 0.86 | PTPN1 (0.41) | ELANEPTPN1HPGDSGSK3BL3MBTL1 | |
| SCHEMBL19122203 | 0.79 | ELANE (0.53) | ELANEMAPTKMT2AMEN1KDM4E | |
| SCHEMBL32665166 | 0.77 | ELANE (0.52) | ELANEL3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL32665145 | 0.76 | PTPN1 (0.41) | PTPN1HPGDSGSK3BALDH1A1 | |
| SCHEMBL29419354 | 0.75 | HPGDS (0.65) | PTPN1HPGDSL3MBTL1NPC1KMT2A | |
| SCHEMBL169081 | 0.75 | HPGDS (0.65) | PTPN1HPGDSL3MBTL1NPC1KMT2A | |
| SCHEMBL21034056 | 0.75 | L3MBTL1 (0.67) | ELANEL3MBTL1MAPTKMT2APOLB | |
| SCHEMBL30634443 | 0.75 | PTPN1 (0.46) | PTPN1HPGDSGSK3BMAPTNPC1 | |
| SCHEMBL29585736 | 0.75 | PTPN1 (0.46) | PTPN1HPGDSGSK3B | |
| SCHEMBL2098762 | 0.75 | PTPN1 (0.46) | PTPN1HPGDSGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ELANE 1276/4885PTPN1 4150/4885HPGDS 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.