Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 13/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665391 | 0.90 | CHRM4 (0.56) | CHRM4CHRM2EPHX2CHRM1 | |
| SCHEMBL4703208 | 0.87 | CHRM4 (0.56) | CHRM4CHRM2 | |
| SCHEMBL12321963 | 0.85 | CKS1B (0.53) | CHRM4YAP1PRMT5 | |
| SCHEMBL32665269 | 0.81 | CKS1B (0.55) | CHRM4EPHX2YAP1PRMT5 | |
| SCHEMBL30258725 | 0.81 | MAPT (0.51) | YAP1 | |
| SCHEMBL2308072 | 0.81 | SIGMAR1 (0.59) | — | |
| SCHEMBL32665123 | 0.81 | ACACB (0.52) | YAP1PRMT5 | |
| SCHEMBL16399970 | 0.79 | HTT (0.56) | YAP1 | |
| SCHEMBL805498 | 0.79 | SIRT2 (0.52) | CHRM4 | |
| SCHEMBL803459 | 0.79 | ACHE (0.67) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CHRM4 4725/4885CHRM2 4716/4885LTA4H 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.