Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665137 | 0.87 | HRH3 (0.36) | CXCR3MMP1MMP9MMP13ADAM17 | |
| SCHEMBL32665569 | 0.86 | OPRM1 (0.44) | OPRM1CHRM2DRD2ALDH1A1CHRM3 | |
| SCHEMBL32665061 | 0.86 | KCNH2 (0.38) | CCR8KCNH2CXCR3MMP1MMP9 | |
| SCHEMBL32665454 | 0.83 | FFAR4 (0.38) | SLC6A2SLC6A3ALDH1A1USP2CYP3A4 | |
| SCHEMBL32665432 | 0.83 | NPSR1 (0.36) | KCNH2SIGMAR1CHRM2DRD2HRH1 | |
| SCHEMBL32665089 | 0.83 | DOCK5 (0.35) | CXCR3SIGMAR1DRD3ALDH1A1MAPK1 | |
| Formic Acid SCHEMBL32665547 | 0.82 | OPRM1 (0.41) | CCR8OPRM1FAAHCHRM2DRD2 | |
| SCHEMBL32665228 | 0.79 | CHRM2 (0.46) | OPRM1SIGMAR1CHRM2DRD2DRD3 | |
| SCHEMBL32665186 | 0.79 | MAPK1 (0.41) | ALDH1A1USP2CYP3A4CYP2D6MAPK1 | |
| SCHEMBL32665507 | 0.73 | MGLL (0.49) | FAAHALDH1A1MAPK1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CCR8 1123/4885KCNH2 4668/4885CXCR3 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.