SCHEMBL32665951

SCHEMBL32665951

Fc1ccc(CNC2=NCCN2)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.54
APOBEC3A P31941 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
WDR5 P61964 15/20 0.48
ADRA2A P08913 1/20 0.45
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29315350 1.00 LMNA (0.55) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL13907367 0.83 LMNA (0.53) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL560405 0.82 LMNA (0.71) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL17186490 0.78 PTGIR (0.61) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL8146510 0.77 LMNA (0.58) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
Hydrochloric Acid SCHEMBL18605409 0.77 PTGIR (0.59) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
SCHEMBL13063071 0.77 LMNA (0.64) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
Iodide SCHEMBL3168283 0.76 LMNA (0.60) LMNAGAAAPOBEC3ACTDSP1APOBEC3G
Hydrochloric Acid SCHEMBL4687702 0.75 ADRA2A (0.64) ADRA2AADRA2BADRA2C
SCHEMBL561403 0.74 LMNA (0.62) LMNAGAAAPOBEC3ACTDSP1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684834-A1 CRYSTALLINE FORMS OF ONCOLOGICALLY ACTIVE IMIPRIDONES AND PROCESS FOR THEIR PREPARATION BRIU GmbH (DE) 2026-01-28 EP disclosed